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Transfusion-Free Complex Cardiac Surgery with Use of Deep Hypothermic Circulatory Arrest in a Preterm 2.96-kg Jehovah's Witness Neonate.
MedLine Citation:
PMID:  22163136     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In neonates, the major obstacle to transfusion-free complex cardiac surgery is the severe hemodilution that can result from the mismatch between the priming volume of the circuit and the patients' blood volume. Herein, we report the case of a 13-day-old, 2.96-kg preterm neonate who had a hypoplastic aortic arch and atrial and ventricular septal defects. At the insistence of her Jehovah's Witness parents, we performed corrective surgery without transfusing homologous blood products-using deep hypothermic circulatory arrest in the process. A specially designed cardiopulmonary bypass circuit with a priming volume of only 95 mL was the key component of an interdisciplinary effort to avoid transfusion while maintaining the patient's safety. To our knowledge, this is the 1st report of the use of deep hypothermic circulatory arrest in blood-transfusion-free surgery to correct congenital heart defects in a small Jehovah's Witness neonate.
Authors:
Michael Huebler; Helmut Habazettl; Wolfgang Boettcher; Hermann Kuppe; Roland Hetzer; Matthias Redlin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital     Volume:  38     ISSN:  1526-6702     ISO Abbreviation:  Tex Heart Inst J     Publication Date:  2011  
Date Detail:
Created Date:  2011-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214622     Medline TA:  Tex Heart Inst J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  562-4     Citation Subset:  IM    
Affiliation:
Departments of Cardiothoracic & Vascular Surgery (Drs. Hetzer and Huebler), Anesthesiology (Drs. Habazettl, Kuppe, and Redlin), and Perfusion (Dr. Boettcher), German Heart Institute, 13353 Berlin; and Institute of Physiology (Dr. Habazettl), Charité University Medicine Berlin, 14195 Berlin; Germany.
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