| Transformed malignant lymphoma from Lennert's lesion is a CD4+ T cell lymphoma: an immunohistochemical study. | |
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MedLine Citation:
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PMID: 2787089 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a case of Lennert's lesion terminating in T cell non-Hodgkin's lymphoma (NHL). A 53-year-old woman showed inguinal lymphadenopathy. This was histologically interpreted as toxoplasmic lymphadenitis. However, Lennert's lesion was diagnosed in subsequent biopsies. Because additional lymphadenopathy and constitutional symptoms were absent, anti-neoplastic therapy was not given. During the five and a half years after the initial biopsy, generalized lymphadenopathy and constitutional symptoms developed. Histological examination of the cervical lymph node disclosed NHL, diffuse, large cell type. Transformed lymphoma cells were confirmed to be of peripheral T cell origin with a helper/inducer phenotype. We speculate that some cases of Lennert's lesion have a potentiality of spontaneous transformation into high grade malignant lymphoma associated with disappearance of epithelioid histiocytes. |
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Authors:
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A Ohsaka; K Saito; S Mori; S Sakamoto; Y Miura |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society Volume: 52 ISSN: 0001-5806 ISO Abbreviation: Nippon Ketsueki Gakkai Zasshi Publication Date: 1989 Feb |
Date Detail:
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Created Date: 1989-08-10 Completed Date: 1989-08-10 Revised Date: 2011-07-28 |
Medline Journal Info:
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Nlm Unique ID: 2984803R Medline TA: Nihon Ketsueki Gakkai Zasshi Country: JAPAN |
Other Details:
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Languages: eng Pagination: 63-70 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antigens, Differentiation, T-Lymphocyte
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analysis Cell Transformation, Neoplastic Female Humans Immunohistochemistry Lymphoma, Non-Hodgkin / diagnosis*, pathology Middle Aged T-Lymphocytes |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Differentiation, T-Lymphocyte |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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