| Transfer of cholesterol by the NPC team. | |
| | |
MedLine Citation:
|
PMID: 20674853 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
|
The mechanisms of intracellular cholesterol transport are largely unknown. In this issue of Cell Metabolism, Wang et al. (2010) identify amino acid residues on the lumenal lysosomal protein Niemann-Pick C2 (NPC2) that are required for intralysosomal transfer of endocytosed cholesterol to membrane-bound NPC1 via a process that avoids movement of hydrophobic cholesterol through the aqueous phase. |
| | |
Authors:
|
Jean E Vance |
Related Documents
:
|
11227043 - Novel approaches to treating cardiovascular disease: lessons from tangier disease. 16284193 - Assembly of high-density lipoprotein. 2181083 - Modulation of selenium-dependent glutathione peroxidase by perfluorodecanoic acid in ra... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Cell metabolism Volume: 12 ISSN: 1932-7420 ISO Abbreviation: Cell Metab. Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-08-02 Completed Date: 2010-11-22 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101233170 Medline TA: Cell Metab Country: United States |
Other Details:
|
Languages: eng Pagination: 105-6 Citation Subset: - |
Copyright Information:
|
Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Group on Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, AB T6G 2S2, Canada. jean.vance@ualberta.ca |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: "Homeopathy: Ex nihilo fit nihil"?
Next Document: A clock ticks in pancreatic beta cells.