Document Detail

Transesophageal left ventricular posterior wall potential in heart failure patients with biventricular pacing.
MedLine Citation:
PMID:  17408376     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Biventricular (BV) pacing is an established therapy for heart failure (HF) patients with intraventricular conduction delay, but not all patients improved clinically. We investigated the interventricular delay (IVD) by means of the transesophageal left ventricular posterior wall potential (LVPWP).
MATERIALS AND METHODS, AND RESULTS: A total of 18 HF patients (age 62+/-9 years; 15 males) with NYHA class 3.1+/-0.3, LV ejection fraction 22+/-7%, left bundle branch block and a QRS duration (QRSD) of 171+/-27 ms were analyzed using transesophageal LVPWP before implantation of a BV pacing device. The median follow up was 14+/-14 months. In 14 responders, IVD was 81+/-25 ms with a QRSD/IVD ratio of 2.2+/-0.3 with reclassification of NYHA class 3.1+/-0.3 to 2.0+/-0.5 (p<0.001) and an increase in LV ejection fraction from 22+/-7% to 36+/-11% (p=0.001) during long-term BV pacing. In four non-responders, transesophageal IVD was significantly smaller at 30+/-11 ms (p=0.001).
CONCLUSION: Transesophageal IVD may be a useful method to detect responders to BV pacing. Transesophageal LVPWP may be a simple and useful technique to detect clinical responders to BV pacing in HF patients.
Matthias Heinke; Ralf Surber; Helmut Kühnert; Gudrun Dannberg; Dirk Prochnau; Hans R Figulla
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Biomedizinische Technik. Biomedical engineering     Volume:  52     ISSN:  0013-5585     ISO Abbreviation:  Biomed Tech (Berl)     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-05     Completed Date:  2007-06-19     Revised Date:  2013-07-15    
Medline Journal Info:
Nlm Unique ID:  1262533     Medline TA:  Biomed Tech (Berl)     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  173-9     Citation Subset:  IM    
Department of Internal Medicine I, Cardiology Division, Friedrich Schiller University Jena, Jena, Germany.
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MeSH Terms
Cardiac Output, Low / complications,  diagnosis,  physiopathology*,  prevention & control*
Cardiac Pacing, Artificial / methods*
Electrocardiography / methods*
Heart Conduction System / physiopathology*
Middle Aged
Treatment Outcome
Ventricular Dysfunction, Left / diagnosis,  etiology,  physiopathology*

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