Document Detail


Transesophageal echocardiographic demonstration of resolution of mitral vegetations after warfarin in a patient with the primary antiphospholipid syndrome.
MedLine Citation:
PMID:  7640017     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 16-year-old girl with multiple cerebral infarcts was reported to have a normal transthoracic echocardiogram, but transesophageal echocardiography revealed vegetations on the atrial surfaces of both mitral leaflets at their line of closure. Blood cultures were negative, and prolonged treatment with intravenous antibiotics produced no echocardiographic improvement in the appearance of the vegetations. A diagnosis of primary antiphospholipid syndrome was made subsequently, although test results for this condition had initially been normal. Serial transesophageal echocardiograms showed complete resolution of the vegetations but some persistent thickening of the mitral leaflets, after warfarin therapy for 9 months. We suggest that in patients with culture-negative endocardial vegetations, specific tests should be performed for the primary antiphospholipid syndrome and a therapeutic trial of warfarin should be undertaken before contemplating heart surgery.
Authors:
R A Skyrme-Jones; C A Wardrop; C M Wiles; A G Fraser
Related Documents :
23964297 - Spontaneous coronary artery dissection mimicking coronary spasm diagnosed by intravascu...
7887707 - Comparison of the carpentier and duran prosthetic rings used in mitral reconstruction.
7438577 - Unusual echocardiographic appearances attributable to submitral calcification simulatin...
22014427 - Does the revised appropriate use criteria for echocardiography represent an improvement...
24069057 - Tongxinluo improves cardiac function and ameliorates ventricular remodeling in mice mod...
6477387 - The relationship between myocardial oxygen consumption and total work obtained by a new...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  8     ISSN:  0894-7317     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:    1995 May-Jun
Date Detail:
Created Date:  1995-09-21     Completed Date:  1995-09-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  251-6     Citation Subset:  IM    
Affiliation:
Department of Cardiology, University of Wales College of Medicine, Heath Park, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Antiphospholipid Syndrome / complications,  drug therapy,  ultrasonography*
Cerebral Infarction / complications
Echocardiography, Transesophageal*
Female
Heart Valve Diseases / drug therapy,  etiology,  ultrasonography*
Humans
Mitral Valve / ultrasonography*
Warfarin / therapeutic use*
Chemical
Reg. No./Substance:
81-81-2/Warfarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The utility of transesophageal echocardiography in the management of renal cell carcinoma with intra...
Next Document:  The spectrum of left ventricular-right atrial communications in the adult: essentials of echocardiog...