Document Detail

Transection of subfornical organ neural connections diminishes the pressor response to intravenously infused angiotensin II.
MedLine Citation:
PMID:  6626986     Owner:  NLM     Status:  MEDLINE    
Knife-cut lesions were used to assess the participation of the subfornical organ (SFO) in the central pressor action of intravenously administered angiotensin. Knife-cuts of the ventral stalk of the SFO significantly attenuated pressor responses during infusion of 3 doses of angiotensin, although responses to bolus injections were unaffected. These results are consistent with previous work in implicating the SFO as an important mediator of the central pressor action of circulating angiotensin.
R W Lind; L E Ohman; M B Lansing; A K Johnson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Brain research     Volume:  275     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1983 Sep 
Date Detail:
Created Date:  1983-12-20     Completed Date:  1983-12-20     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  361-4     Citation Subset:  IM    
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MeSH Terms
Angiotensin II / pharmacology*
Blood Pressure / drug effects*
Dose-Response Relationship, Drug
Drinking Behavior / drug effects*
Neurosecretory Systems / physiology*
Rats, Inbred Strains
Subfornical Organ / physiology*
Reg. No./Substance:
11128-99-7/Angiotensin II

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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