| Transdermal rotigotine for the perioperative management of Parkinson's disease. | |
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MedLine Citation:
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PMID: 20535621 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Continuous delivery of antiparkinsonian medication during a perioperative period is desirable to avoid 'off'-symptom complications in surgical patients with concomitant Parkinson's disease (PD). Fourteen PD patients undergoing surgery under general anesthesia were switched from oral dopaminergic medication to transdermally delivered 24-h rotigotine (median dose 12 mg/24 h) for the perioperative period. Rotigotine treatment was considered feasible by patients, their anesthesiologists and neurologists with good control of PD symptoms and easy switching and re-switching of PD medication. |
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Authors:
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Ullrich Wüllner; Jan Kassubek; Per Odin; Michael Schwarz; Markus Naumann; Hermann-Josef Häck; Babak Boroojerdi; Heinz Reichmann; |
Publication Detail:
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Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't Date: 2010-06-10 |
Journal Detail:
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Title: Journal of neural transmission (Vienna, Austria : 1996) Volume: 117 ISSN: 1435-1463 ISO Abbreviation: J Neural Transm Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-02 Completed Date: 2010-10-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9702341 Medline TA: J Neural Transm Country: Austria |
Other Details:
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Languages: eng Pagination: 855-9 Citation Subset: IM |
Affiliation:
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Department of Neurology, University Bonn, Sigmund-Freud-Strasse 25, 53105, Bonn, Germany. wuellner@uni-bonn.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Cutaneous Aged Aged, 80 and over Anesthesia, General Anesthesiology Attitude of Health Personnel Dopamine Agonists / administration & dosage*, therapeutic use Feasibility Studies Female Humans Male Middle Aged Neurology Parkinson Disease / drug therapy*, psychology, surgery* Perioperative Care* Physicians / psychology Prospective Studies Tetrahydronaphthalenes / administration & dosage*, therapeutic use Thiophenes / administration & dosage*, therapeutic use Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Dopamine Agonists; 0/Tetrahydronaphthalenes; 0/Thiophenes; 92206-54-7/N 0437 |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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