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Transdermal fentanyl: little absorption in two patients with systemic sclerosis?
MedLine Citation:
PMID:  15102255     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Two patients suffering from systemic sclerosis (SSc) were treated with the 25 micro/hr transdermal fentanyl patch for pain from either deltoid muscle tendinitis of the left arm or from ischemia of the left-hand thumb. When the medication was changed to either oral morphine or oral methadone, the effects did not correspond to the drug conversion table. These findings suggest that patients with SSc and other systemic skin diseases may be at risk for limited absorption of transdermal fentanyl. In contrast, no restriction of the absorption of transdermal testosterone was observed.
Authors:
M Karst; M Fink; T Wagner; I Conrad
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pain medicine (Malden, Mass.)     Volume:  2     ISSN:  1526-2375     ISO Abbreviation:  Pain Med     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2004-04-22     Completed Date:  2005-04-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100894201     Medline TA:  Pain Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  225-7     Citation Subset:  -    
Affiliation:
Department of Anesthesiology, Pain Clinic, Hannover Medical School, Germany. Karst.Matthias@MH-Hannover.de
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