Document Detail

Transcutaneous oxygen measurements under hyperbaric oxygen conditions as a predictor for healing of problem wounds.
MedLine Citation:
PMID:  12398146     Owner:  NLM     Status:  MEDLINE    
Controversy exists as to what transcutaneous oxygen (P(tc)O2) levels are required for wound healing and what role hyperbaric oxygen has for this. Current information suggests that 30 to 40 mmHg juxta-wound oxygen tensions in room air are required. We recorded P(tc)O2 measurements in room air and with hyperbaric oxygen in 190 patients with foot wounds; then looked retrospectively and prospectively whether there was any effect on healing. Transcutaneous oxygen measurements under hyperbaric oxygen conditions defined a responder group (P(tc)O2 > 200 mmHg) with a sensitivity of 0.80 and a positive predictive value of 0.88 for healing, regardless of room air measurements when hyperbaric oxygen was used as an adjunct to wound management. This information helps to objectify the indications for hyperbaric oxygen and predict healing especially in those patients with problem wounds of the foot and ankle.
Michael B Strauss; Brandon J Bryant; George B Hart
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Foot & ankle international     Volume:  23     ISSN:  1071-1007     ISO Abbreviation:  Foot Ankle Int     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-10-25     Completed Date:  2002-11-12     Revised Date:  2014-08-27    
Medline Journal Info:
Nlm Unique ID:  9433869     Medline TA:  Foot Ankle Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  933-7     Citation Subset:  IM    
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MeSH Terms
Ankle Injuries / blood,  physiopathology,  therapy
Blood Gas Monitoring, Transcutaneous / methods*
Foot Injuries / blood,  physiopathology,  therapy
Hyperbaric Oxygenation*
Predictive Value of Tests
Prospective Studies
Retrospective Studies
Wound Healing*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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