Document Detail


Transcutaneous bilirubinometry in preterm infants receiving phototherapy.
MedLine Citation:
PMID:  15838745     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The accuracy of transcutaneous bilirubin (TcB) measurements obtained with a Bilicheck device in 70 preterm neonates before phototherapy and during phototherapy from the exposed and unexposed skin of the forehead (under the eye patch) was evaluated by comparing the TcB with the total serum bilirubin (TSB) that was performed within +/- 30 minutes of the TcB measurements. The correlation and proportion of similar, overestimated, and underestimated paired TcB/TSB measurements was calculated. A TSB point estimate of +/- 1.5 mg/dL was used for comparison of differences between the TcB and TSB. There was weaker correlation between TcB and TSB when the TcB was obtained from the exposed skin (r = 0.70; p > 0.05) as compared with an unexposed area (r = 0.77; p < 0.04) or before initiation of phototherapy (r = 0.86; p < 0.01). The TcB measurements from the area unexposed to phototherapy were predominantly (97.2%) in the similar (57%) or overestimation categories (40.2%). A significantly lower proportion of the paired TcB/TSB measurements obtained from exposed area were similar (42%) or overestimated (27%; p < 0.001). More importantly, in 31% of the measurements, the TSB levels were underestimated by the TcB. We conclude that the Bilicheck can be used for the evaluation of bilirubin levels in preterm neonates receiving phototherapy by using the unexposed skin of the forehead (under the eye patch) for TcB measurements; this may significantly reduce the number of blood draws.
Authors:
Shakuntala Nanjundaswamy; Anna Petrova; Rajeev Mehta; Thomas Hegyi
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  American journal of perinatology     Volume:  22     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-04-19     Completed Date:  2005-07-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  127-31     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Division of Neonatology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903-0019, USA.
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MeSH Terms
Descriptor/Qualifier:
Bilirubin / blood*
Equipment Design
Humans
Infant, Newborn
Infant, Premature*
Jaundice, Neonatal / blood,  therapy
Monitoring, Physiologic / methods
Phototherapy*
Skin / chemistry*
Chemical
Reg. No./Substance:
635-65-4/Bilirubin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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