Document Detail

Transcutaneous bilirubin in predicting hyperbilirubinemia in term neonates.
MedLine Citation:
PMID:  18334790     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the utility of 24 and 48 hours transcutaneous bilirubin (TcB) index for predicting subsequent significant hyperbilirubinemia in healthy term neonates. METHODS: TcB indices were obtained for healthy, breastfed, term AGA newborns at 24 +/- 2, 48 +/- 2 and subsequently at intervals of 24 hours. Neonates with illness, on treatment and positive Direct Coomb's test were excluded. Serum bilirubin levels were obtained whenever indicated. Neonates having serum bilirubin > or = 17 mg/dL were considered as significant hyperbilirubinemia. The 24 and 48 hour TcB indices, as risk predictors for such hyperbilirubinemia were determined. RESULTS: Study included 461 healthy term neonates. The mean birth weight was 2949 (+/- 390) gm and mean gestation of 38.6 (+/- 1.1) weeks. Eight one (17.6%) had significant hyperbilirubinemia. Of 461, 135 (29.3%) had TcB index. CONCLUSION: The 24 and 48 hour TcB indices are predictive for subsequent significant hyperbilirubinemia and can guide clinician in early discharge of healthy term newborns.
Y Ramesh Bhat; Amitha Rao
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  75     ISSN:  0973-7693     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-03-12     Completed Date:  2008-06-05     Revised Date:  2009-11-13    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  119-23     Citation Subset:  IM    
Department of Pediatrics, Kasturba Medical College, Manipal University, Manipal, Udupi District, Karnataka State, India.
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MeSH Terms
Bilirubin / metabolism*
Birth Weight
Hyperbilirubinemia, Neonatal / diagnosis*
Infant, Newborn
Infant, Premature
Neonatal Screening / methods*
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity
Skin / metabolism*
Time Factors
Reg. No./Substance:
Comment In:
Indian J Pediatr. 2009 Oct;76(10):1075; author reply 1075-6   [PMID:  19907952 ]

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