Document Detail


Transcriptional repressors: shutting off gene expression at the source affects developmental dynamics.
MedLine Citation:
PMID:  22032193     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Developmental networks feature genes interlinked by transcriptional activation and repression. A new study indicates that repressors can 'shut the door' to newly initiating polymerases, allowing longer target genes to produce latent transcripts after shorter genes have been effectively silenced.
Authors:
David N Arnosti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current biology : CB     Volume:  21     ISSN:  1879-0445     ISO Abbreviation:  Curr. Biol.     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107782     Medline TA:  Curr Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  R859-60     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Biochemistry and Molecular Biology, and Program in Quantitative Biology, Michigan State University, East Lansing, MI 48824, USA.
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