| Transcriptional, post-transcriptional and epigenetic control of porcine oocyte maturation and embryogenesis. | |
| | |
MedLine Citation:
|
PMID: 19848279 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Embryogenesis is a complex process that is controlled at various levels. As new discoveries are made about molecular mechanisms that control development in other species, it is apparent that these same mechanisms regulate pig embryogenesis as well. Methylation of DNA and modification of histones regulate transcription, and mechanisms such as ubiquitinization, autophagy and microRNAs regulate development post-transcriptionally. Each of these systems of regulation is highly dynamic in the early embryo. A better understanding of each of these levels of regulation can provide tools to potentially improve the reproductive process in pigs, to improve methods of creating pig embryos and cloned embryos in vitro, and to provide markers for predicting developmental competence of the embryo. |
| | |
Authors:
|
R S Prather; J W Ross; S Clay Isom; J A Green |
Related Documents
:
|
16660249 - Preformed messenger rnas and early wheat embryo germination. 15862559 - Ontogeny of osteonectin expression in embryos and larvae of sea bream (sparus auratus). 17008449 - The yolk syncytial layer regulates myocardial migration by influencing extracellular ma... 19651849 - Silencing cenpf in bovine preimplantation embryo induces arrest at 8-cell stage. 17913529 - Ethanol teratogenesis in japanese medaka: effects at the cellular level. 22360389 - Temporal requirements of heat shock factor-1 for longevity assurance. 12370739 - Transforming growth factor alpha, amphiregulin and cripto-1 are frequently expressed in... 18202089 - External suppression causes the low expression of the cosmc gene in iga nephropathy. 12512839 - Plasma leptin and leptin receptor expression in childhood acute lymphoblastic leukemia. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review |
Journal Detail:
|
Title: Society of Reproduction and Fertility supplement Volume: 66 ISSN: - ISO Abbreviation: Soc Reprod Fertil Suppl Publication Date: 2009 |
Date Detail:
|
Created Date: 2009-10-23 Completed Date: 2010-03-11 Revised Date: 2011-09-26 |
Medline Journal Info:
|
Nlm Unique ID: 101295315 Medline TA: Soc Reprod Fertil Suppl Country: England |
Other Details:
|
Languages: eng Pagination: 165-76 Citation Subset: IM |
Affiliation:
|
Division of Animal Sciences, University of Missouri, Columbia, MO 65211, USA. PratherR@Missouri.Edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Embryonic Development / genetics*, physiology Epigenesis, Genetic / physiology Female MicroRNAs / physiology Oogenesis / genetics*, physiology RNA Processing, Post-Transcriptional / physiology Swine / physiology* Transcription, Genetic / physiology |
| Grant Support | |
ID/Acronym/Agency:
|
R01 RR013438-11/RR/NCRR NIH HHS; RR013438/RR/NCRR NIH HHS; RR018877/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/MicroRNAs |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Intra-follicular regulatory mechanisms in the porcine ovary.
Next Document: Ovarian responses to lactation management strategies.