Document Detail


Transcriptional control of natural killer cell differentiation and function.
MedLine Citation:
PMID:  21863375     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Gene expression can be modulated depending on physiological and developmental requirements. A multitude of regulatory genes, which are organized in interdependent networks, guide development and eventually generate specific phenotypes. Transcription factors (TF) are a key element in the regulatory cascade controlling cell fate and effector functions. In this review, we discuss recent data on the diversity of TF that determine natural killer (NK) cell fate and NK cell function.
Authors:
Alfonso Martín-Fontecha; Graham M Lord; Hugh J M Brady
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-24
Journal Detail:
Title:  Cellular and molecular life sciences : CMLS     Volume:  -     ISSN:  1420-9071     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9705402     Medline TA:  Cell Mol Life Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Medical Research Council (MRC) Centre for Transplantation, Guy's Hospital , King's College London, 5th floor Tower Wing, London, SE1 9RT, UK, alfonso.martin-fontecha@kcl.ac.uk.
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