Document Detail


Transcriptional control of SSL1, a gene controlling alpha-specific inactivation of a-factor in Saccharomyces cerevisiae.
MedLine Citation:
PMID:  2187738     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The SSL1 gene of S. cerevisiae which is involved in the cell-type specific recovery of mating type alpha cells from cell cycle arrest by the mating hormone a-factor has been cloned as a 1 kb Sau3A fragment in a complementing plasmid from a library of S. cerevisae genomic DNA. Disruption of this gene in wild-type alpha-cells results in the ssl1- phenotype which is characterized by an extreme sensitivity to a-factor. Transcription analysis revealed that the SSL1 gene is transcribed only in MAT alpha cells but not in MAT alpha or diploid (MAT alpha/MAT alpha) cells defining it as a member of the set of alpha-specific genes.
Authors:
M Steden; W Duntze
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  FEMS microbiology letters     Volume:  56     ISSN:  0378-1097     ISO Abbreviation:  FEMS Microbiol. Lett.     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-06-27     Completed Date:  1990-06-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7705721     Medline TA:  FEMS Microbiol Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  229-32     Citation Subset:  IM    
Affiliation:
Institut für Physiologische Chemie, Ruhr-Universität Bochum, F.R.G.
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MeSH Terms
Descriptor/Qualifier:
Blotting, Southern
Gene Expression Regulation, Fungal*
Genes, Fungal*
Genes, Mating Type, Fungal*
Genes, Regulator
Peptides / genetics*
Restriction Mapping
Saccharomyces cerevisiae / genetics*
Transcription, Genetic*
Chemical
Reg. No./Substance:
0/Peptides; 61194-02-3/mating factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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