Document Detail


Transcription: new insights from studies on Archaea.
MedLine Citation:
PMID:  7482778     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Molecular-genetic analyses have revealed that the Archaea (archaebacteria) are phylogenetically distinct from both eukaryotes and eubacteria. Archaea lack nuclei and resemble eubacteria in morphology and genomic organization, but their molecular design shares many features with eukaryotes. Here, we review recent work that indicates that the archaeal transcriptional machinery is strikingly similar to the RNA polymerase I, II, and III systems of eukaryotic cell nuclei. These findings provide important insights into the evolution of the transcriptional apparatus.
Authors:
P Baumann; S A Qureshi; S P Jackson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Trends in genetics : TIG     Volume:  11     ISSN:  0168-9525     ISO Abbreviation:  Trends Genet.     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-11-30     Completed Date:  1995-11-30     Revised Date:  2009-09-29    
Medline Journal Info:
Nlm Unique ID:  8507085     Medline TA:  Trends Genet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  279-83     Citation Subset:  IM    
Affiliation:
Imperial Cancer Research Fund, Clare Hall Laboratories, Herts., UK.
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MeSH Terms
Descriptor/Qualifier:
Archaea / genetics*
Evolution, Molecular
Gene Expression Regulation, Bacterial
Genes, Bacterial
Transcription Factors / chemistry
Transcription, Genetic*
Grant Support
ID/Acronym/Agency:
//Wellcome Trust
Chemical
Reg. No./Substance:
0/Transcription Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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