Document Detail


Transcranial cerebral oximetry and transcranial doppler sonography in patients with ruptured cerebral aneurysms and delayed cerebral vasospasm.
MedLine Citation:
PMID:  17901860     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Vasospasm is a major cause of ischemic neurological deficits developing after subarachnoid hemorrhage. The goal was to identify hemodynamic changes and the presence of clinical vasospasm in patients suffering from subarachnoid hemorrhage secondary to ruptured intracranial aneurysms. MATERIAL/METHODS: Pre- and postoperative serial transcranial cerebral oximetry and transcranial doppler sonography (TCD) examinations were performed in 75 patients operated for aneurysmal subarachnoid hemorrhage. RESULTS: No significant difference (p=0.14) was found in the levels of regional oxygen saturation (rSO2) between patients with vasospasm and those without. In patients who developed clinical vasospasm, the blood flow velocity values were significantly higher compared with those who did not (127.5+/-2.7 versus 92.5+/-1.2 cm/sec, p<0.001). In six patients with clinical vasospasm and low TCCO measurements, the use of triple-H therapy led to oxygen saturation increment and clinical improvement. CONCLUSIONS: Transcranial cerebral oximetry seems to be of limited value for the detection of vasospasm in patients with subarachnoid hemorrhage. However, it may be useful in estimating the clinical impact of triple-H therapy in such patients.
Authors:
Constantine Constantoyannis; George C Sakellaropoulos; George C Kagadis; Paraskevi F Katsakiori; Theodore Maraziotis; George C Nikiforidis; Nikolas Papadakis
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical science monitor : international medical journal of experimental and clinical research     Volume:  13     ISSN:  1234-1010     ISO Abbreviation:  Med. Sci. Monit.     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-09-28     Completed Date:  2007-11-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9609063     Medline TA:  Med Sci Monit     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  MT35-40     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, University of Patras, School of Medicine, Rion, Greece. cconst@med.upatras.gr
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aneurysm, Ruptured / ultrasonography*
Female
Humans
Intracranial Aneurysm / complications*,  ultrasonography*
Male
Middle Aged
Oximetry / methods*
Oxygen / metabolism
Ultrasonography, Doppler, Transcranial / methods*
Vasospasm, Intracranial / complications*,  ultrasonography*
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Neural complexity, dissociation and schizophrenia.
Next Document:  Recent advances in tumor hypoxia: tumor progression, molecular mechanisms, and therapeutic implicati...