Document Detail


Transcortical streaming potentials are generated by circulatory pressure gradients in living canine tibia.
MedLine Citation:
PMID:  2293626     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Electrical potentials associated with the pulse pressure have been observed in a canine tibia model in vivo. As the medullary pressure rises during pulsing, the periosteal bone surface becomes positive with respect to the endosteal surface. This pattern is consistent with streaming potentials generated by outward flow of fluid through bone with a negatively charged matrix (negative zeta potential). Both the medullary pressure and electric potential oscillations are halted by occlusion of the femoral artery. Furthermore, systemic administration of epinephrine decreases the amplitude of the medullary pressure and the electric potential by the same fraction. Streaming potentials generated by blood flow are distinct from those generated by mechanical deformation and may have additional significance in relation to fracture healing and/or etiology of osteoporosis.
Authors:
M W Otter; V R Palmieri; G V Cochran
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of orthopaedic research : official publication of the Orthopaedic Research Society     Volume:  8     ISSN:  0736-0266     ISO Abbreviation:  J. Orthop. Res.     Publication Date:  1990 Jan 
Date Detail:
Created Date:  1990-01-24     Completed Date:  1990-01-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8404726     Medline TA:  J Orthop Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  119-26     Citation Subset:  IM    
Affiliation:
Orthopaedic Engineering and Research Center, Helen Hayes Hospital, West Haverstraw, New York 10993.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure*
Cattle
Dogs
Electrophoresis
Extremities / physiology
Femoral Artery
Femur / physiology
Injections, Intra-Arterial
Movement
Pulse
Sodium Chloride / pharmacology
Tibia / physiology*
Chemical
Reg. No./Substance:
7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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