Document Detail

Transcatheter device occlusion of multiple large pulmonary arteriovenous malformations in two symptomatic pediatric patients.
MedLine Citation:
PMID:  18377503     Owner:  NLM     Status:  MEDLINE    
Pulmonary arteriovenous malformations (AVMs) large enough to lead to clinically significant cyanosis are rare in the pediatric population. To date, there has been some experience with transcatheter embolization of pulmonary AVMs in children, primarily with coils or balloons. Herein, we report 2 cases of children who were progressively symptomatic and had physical manifestations of hypoxemia arising from large pulmonary AVMs. Both improved after successful catheter-based placement of multiple occlusion devices (Amplatzer vascular plugs) in the pulmonary arterial segments feeding the AVMs produced a rapid, sustained increase in oxygen saturations, and a subsequent amelioration of their symptoms. This represents the first case series of multiple Amplatzer vascular plugs placed into numerous arteriovenous formations, exclusively in children. This approach represents an additional nonsurgical option for children or adults with symptomatic pulmonary AVMs.
Alexander R Ellis; Anthony M Hlavacek; Varsha M Bandisode; Jeremy M Ringewald
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Congenital heart disease     Volume:  1     ISSN:  1747-0803     ISO Abbreviation:  -     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2008-04-01     Completed Date:  2008-05-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101256510     Medline TA:  Congenit Heart Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  327-31     Citation Subset:  IM    
South Carolina Children's Heart Center, The Medical University of South Carolina, Charleston, SC 29425, USA.
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MeSH Terms
Anoxia / etiology,  therapy
Arteriovenous Malformations / complications,  diagnosis,  therapy*
Blood Vessel Prosthesis
Blood Vessel Prosthesis Implantation / instrumentation*,  methods*
Equipment Design
Heart Catheterization
Pulmonary Artery / abnormalities*
Pulmonary Veins / abnormalities*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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