Document Detail

Transcatheter closure of ventricular septal defects using the Rashkind device: initial experience.
MedLine Citation:
PMID:  10348565     Owner:  NLM     Status:  MEDLINE    
We report our initial experience with transcatheter closure of ventricular septal defects (VSD) using the Rashkind device. Transcatheter closure of 25 VSDs was attempted in 16 patients with a median age of 2 (range 0.1-4) years and a median weight of 11 (range 4.1-19) kg. The location of the VSDs was apical in 14, midmuscular in 8, and anterior muscular in 3. Five patients had complex heart lesions, 10 patients had associated defects, including perimembranous VSD, atrial septal defect, patent ductus arteriosus, and coarctation of aorta. The remaining patient had isolated multiple muscular VSDs. The surgical repair of VSDs was a high-risk option in all the patients. Of the 25 attempted closures, 22 devices were placed successfully. Nine patients had a single device, four patients had two devices each and one patient had a total of five devices placed. In two patients attempts to close three VSDs were associated with major problems/death. Fourteen patients have been followed up for at least 1 year and all are doing well. Five patients, who otherwise remain asymptomatic, have a trace residual shunt. The fluoroscopy time ranged from 51 to 205 min (median 110) and the procedure time 120 to 300 min (median 200). The transcatheter closure of VSDs acts as a palliation as well as a definitive therapeutic modality in some patients with surgically inaccessible VSDs. Deployment of multiple devices in a patient is feasible. Increased experience may diminish the initial rate of complications.
S Janorkar; T Goh; J Wilkinson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  46     ISSN:  1522-1946     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-07-01     Completed Date:  1999-07-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  43-8     Citation Subset:  IM    
Department of Cardiology, Royal Children's Hospital, Melbourne, Victoria, Australia.
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MeSH Terms
Child, Preschool
Echocardiography, Transesophageal
Heart Catheterization* / methods
Heart Septal Defects, Ventricular / therapy*,  ultrasonography
Prostheses and Implants*
Prosthesis Design
Retrospective Studies
Treatment Outcome
Comment In:
Catheter Cardiovasc Interv. 1999 Jan;46(1):49-50   [PMID:  10348566 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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