Document Detail

Transcatheter closure of small-to-large patent ductus arteriosus with different devices: queries and challenges.
MedLine Citation:
PMID:  17620673     Owner:  NLM     Status:  MEDLINE    
Transcatheter closure of patent ductus arteriosus (PDA) has been in place for more than three decades. We share our experience with the newer devices. PATIENTS AND METHODS: Ninety-eight patients, with a mean age of 64 +/- 11 months (range 7 months to 54 years), underwent attempted transcatheter closure of PDA. Thirty-seven patients were infants and 10 were adults. Two patients had residual PDA after surgical ligation. There were 66 females and 32 males. RESULTS: Sixty-six patients were symptomatic and 32 were asymptomatic. Cardiac catheterization showed significant pulmonary hypertension in 18. The mean size of the PDA on aortogram was 3.1 +/- 1.4 mm (range 1.1 to 11 mm). Seven patients were referred for surgical ligation. The PDAs of 37 patients were closed using coil devices, 52 with Amplatzer duct occluders (ADO) and two with Amplatzer muscular VSD devices. One patient had a very large PDA which was embolized and retrieved surgically. One patient required occlusion with two coils. The occlusion rate in the catheterization laboratory with coils was 84 +/- 7%, and 83% with ADO. After 1 week, the occlusion rate for coils was 96%, and 99% with ADO. One patient with a large PDA requiring a 14/12 ADO was left with a mild gradient of 9 mmHg in the aorta at the end of the procedure. None of our patients had stenosis of the left pulmonary artery. CONCLUSION: Transcatheter closure of PDA is the preferred alternative to surgical ligation, which should be reserved for small infants and premature babies or large unfavorably-shaped ducts.
Mehnaz Atiq; Nadeem Aslam; Khawar A Kazmi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  19     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-07-10     Completed Date:  2007-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  295-8     Citation Subset:  IM    
Section of Cardiology, Department of Pediatrics, The Aga Khan University Hospital, Karachi, Pakistan.
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MeSH Terms
Cardiac Surgical Procedures / methods*
Child, Preschool
Ductus Arteriosus, Patent / diagnosis,  surgery*
Echocardiography, Doppler, Color
Follow-Up Studies
Heart Catheterization*
Middle Aged
Prosthesis Design
Prosthesis Implantation / instrumentation*
Retrospective Studies
Severity of Illness Index
Treatment Outcome
Comment In:
J Invasive Cardiol. 2007 Jul;19(7):299-302   [PMID:  17620674 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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