| Transcatheter closure of secundum atrial septal defects with complex anatomy. | |
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MedLine Citation:
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PMID: 15152159 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to evaluate the feasibility, safety and efficacy of transcatheter closure of secundum atrial septal defects (ASD) in patients with complex anatomy. From September 1997 to July 2003, a total of 40 patients (median age, 34 years; 65% female) with complex ASDs, defined as the presence of a large defect (stretched diameter >26 mm) associated with a deficient rim (n=23); multiple defects (n=8); a multi-fenestrated septum (n=5); and defects associated with an aneurysmal septum irrespective of their size (n=4) underwent closure. The Helex device was used in 4 patients and the Amplatzer in the remaining. Two devices were implanted in 2 patients each. Implantation was unsuccessful in 5 patients, with 4 having large defects associated with a deficient anterior rim and a floppy posterior septum. Occlusion was observed in 22 of 35 patients (63%) immediately after implantation and in 31 (89%) at a mean follow-up of 18+/-9 months. No major complications occurred. Right ventricular end-diastolic dimensions (indexed for body surface area) decreased from 135+/-25% before closure to 124+/-15% 24 hours after closure, and to 92+/-12% after 12 months. Two patients with 2 distant defects and 2 patients with large defects remained with shunts (<4 mm) at the latest visit. Transcatheter closure of complex secundum ASDs was feasible, safe and effective; however, large defects associated with a deficient anterior rim and a floppy posterior septum may not be suitable for this approach. |
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Authors:
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Carlos A C Pedra; Simone R F Pedra; César A Esteves; Renata Cassar; Sérgio C Pontes; Sérgio L N Braga; Valmir F Fontes |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of invasive cardiology Volume: 16 ISSN: 1042-3931 ISO Abbreviation: J Invasive Cardiol Publication Date: 2004 Mar |
Date Detail:
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Created Date: 2004-05-20 Completed Date: 2004-07-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8917477 Medline TA: J Invasive Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 117-22 Citation Subset: IM |
Affiliation:
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Instituto Dante Pazzanese de Cardiologia, Av Dr Dante Pazzanese 500, CEP 04012-180, Sao Paulo, SP, Brazil. cacpedra@uol.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Balloon Occlusion / instrumentation* Blood Vessel Prosthesis Implantation / instrumentation, methods* Child Contrast Media Echocardiography, Transesophageal Feasibility Studies Female Follow-Up Studies Heart Catheterization / methods Heart Septal Defects, Atrial / pathology, surgery*, ultrasonography Humans Male Middle Aged Safety Surgical Instruments |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
| Comments/Corrections | |
Comment In:
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J Invasive Cardiol. 2004 Mar;16(3):123-5
[PMID:
15152160
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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