Document Detail

Transcatheter closure of patent foramen ovale in patients with migraine headache.
MedLine Citation:
PMID:  17107372     Owner:  NLM     Status:  MEDLINE    
Our objective is to review the epidemiology and pathophysiology of migraine headache, its association with patent foramen ovale (PFO), and the impact of PFO closure on migraine. Upon reviewing English-language publications listed in MEDLINE relating to migraine headache, PFO, and transcatheter closure of PFO, we selected case series, retrospective and prospective studies relevant to the topic. Primarily retrospective case-control studies demonstrate a link between PFO closure and improvement of migraine headache. Few prospective data confirm the initial results. However, the only randomized, controlled trial finished to date analyzing the effect of PFO closure on migraine failed to reach its primary outcome of resolution of migraine following the intervention. The evidence of a benefit on migraine headache following PFO closure is not convincing, but certainly intriguing. With currently ongoing trials, more information related to this topic can be expected.
Christian Spies; Rainer Schräder
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of interventional cardiology     Volume:  19     ISSN:  0896-4327     ISO Abbreviation:  J Interv Cardiol     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-19     Completed Date:  2007-01-09     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  8907826     Medline TA:  J Interv Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  552-7     Citation Subset:  IM    
Rush University Medical Center, Section of Cardiology, Chicago, Illinois, USA.
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MeSH Terms
Heart Catheterization / methods*
Heart Septal Defects, Atrial / complications,  surgery*
Migraine Disorders / complications*
Migraine with Aura / complications

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