| Transcatheter arterial chemoembolization for hepatocellular carcinoma in cirrhosis: influence on portal hypertension. | |
| | |
MedLine Citation:
|
PMID: 21546840 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND: Transcatheter arterial chemoembolization (TACE) is a routine treatment for hepatocellular carcinoma in cirrhotic patients. Whether TACE influences the degree of portal hypertension remains uncertain. AIM AND PATIENTS: We retrospectively analyzed the clinical course of 283 TACE to investigate the incidence of variceal bleeding and ascites after the procedure. We also prospectively evaluated portal pressure by hepatic venous portal gradient (HVPG) before and within 3 days by TACE in a group of 15 patients. RESULTS: Before TACE, esophageal varices were present in 125 patients. Variceal bleeding occurred in three (1.5%) and ascites in two (1%) patients during the follow-up post-TACE. Patients with variceal bleeding were significantly older (P=0.019). In 15 patients who underwent portal pressure measurement before and within 3 days by TACE, HVPG was unchanged (mean 13.1 vs. 12.8 mmHg, P>0.05). CONCLUSION: In our series portal hypertension-related complications after TACE were rare and did not result in higher mortality. As TACE did not influence HVPG, the preventive ligation of esophageal varices before TACE does not seem justified. |
| | |
Authors:
|
Chiara Elia; Wilma Debernardi Venon; Davide Stradella; Silvia Martini; Franco Brunello; Alfredo Marzano; Giorgio Saracco; Mario Rizzetto |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-5-4 |
Journal Detail:
|
Title: European journal of gastroenterology & hepatology Volume: - ISSN: 1473-5687 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-5-6 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9000874 Medline TA: Eur J Gastroenterol Hepatol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
aDepartment of Gastrohepatology, San Giovanni Battista Hospital, Turin bS.C. Gastroenterology - San Luigi Gonzaga Hospital, Orbassano, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bipolar disorder and resembling special psychopathological manifestations in multiple sclerosis: a r...
Next Document: Genetic counseling following the detection of hemoglobinopathy trait on the newborn screen is well r...