Document Detail

Transcatheter Intra-arterial Limb Infusion for Extremity Osteosarcoma: Technical Considerations and Outcomes.
MedLine Citation:
PMID:  21767779     Owner:  NLM     Status:  In-Data-Review    
The goal of transcatheter arterial infusion is to achieve better tumor response by delivering chemotherapy directly into the arterial bed supplying a neoplasm. The rationale behind such therapy relies on the potentially increased tumoricidal effect afforded by higher local concentrations of the infused chemotherapic agent(s) combined with longer tissue exposure times. The use of intra-arterial chemotherapy with or without transcatheter embolization before limb salvage surgery has been demonstrated to induce substantial tumor necrosis and reduce intraoperative blood loss. Recent advances in catheter technology have greatly reduced the morbidity associated with the procedure. This article will focus on the technical aspects of intra-arterial chemotherapy for the treatment of extremity osteosarcoma.
Rony Avritscher; Sanaz Javadi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Techniques in vascular and interventional radiology     Volume:  14     ISSN:  1557-9808     ISO Abbreviation:  Tech Vasc Interv Radiol     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-07-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9806675     Medline TA:  Tech Vasc Interv Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  124-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Section of Interventional Radiology, Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, Houston, TX.
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