Document Detail


Transcapsular arterial neovascularization of liver transplants increases the risk of intraoperative bleeding during retransplantation.
MedLine Citation:
PMID:  23350918     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Arterial neovascularization of liver grafts can be a source of significant blood loss during retransplantation. This study evaluated the effect of transcapsular arterial neovascularization on intraoperative blood loss during retransplantation and long-term follow-up. Eleven consecutive patients with transcapsular arterial neovascularization (seven male, four female; nine children, two adults; mean age 12.3 ± 16.3 years) and the same number of matched control patients were analysed. Blood loss was calculated based on transfusion requirements. The volume of transfused units of red blood cells per kilogram bodyweight until hepatectomy and during the entire procedure was significantly higher in patients with neovascularization than in control patients (0.32 ± 0.21 vs. 0.14 ± 0.11, and 0.94 ± 0.83 vs. 0.36 ± 0.38 respectively; P-values 0.027). Neovascularization was associated with extensive intra-abdominal adhesions and a longer operating time until hepatectomy (175.6 ± 52.1 min vs. 124.3 ± 34.9 min, P-value 0.015). Postoperative revisions were performed more frequently in patients with neovessels. Graft survival did not differ between groups. Assessment for transcapsular arterial neovascularization should be included in preoperative Doppler ultrasound protocols to identify patients at risk of a complicated intra- and postoperative course in case of retransplantation.
Authors:
Jochen Herrmann; Uta Herden; Rainer Ganschow; Kay U Petersen; Felix Schmid; Thorsten Derlin; Andreas Koops; Sven Peine; Martina Sterneck; Lutz Fischer; Knut Helmke
Related Documents :
12424538 - Prospective randomized trial to evaluate two delayed granulocyte colony stimulating fac...
20428638 - Description of a widespread outbreak of aseptic meningitis due to echovirus 30 in rio d...
3889248 - Long-term sequelae of group b streptococcal meningitis in infants.
20217128 - Long-term results after transplantation of cd34+ selected (cellpro) versus unselected p...
24579858 - Cost-effectiveness of unicompartmental knee arthroplasty, high tibial osteotomy, and ki...
17352798 - Plasma nevirapine levels, adverse events and efficacy of antiretroviral therapy among h...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-25
Journal Detail:
Title:  Transplant international : official journal of the European Society for Organ Transplantation     Volume:  -     ISSN:  1432-2277     ISO Abbreviation:  Transpl. Int.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908516     Medline TA:  Transpl Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 The Authors Transplant International © 2013 European Society for Organ Transplantation. Published by Blackwell Publishing Ltd.
Affiliation:
Department of Paediatric Radiology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Donation after cardiac death: results of the SUMMA 112 - Hospital 12 de Octubre Program.
Next Document:  Loop-mediated isothermal Amplification (LAMP) based Method for rapid Mushroom Species Identification...