| Transcapillary filtration in lower limbs with deep venous thrombosis; the role of the capillary filtration coefficient. | |
| | |
MedLine Citation:
|
PMID: 2353163 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The capillary filtration coefficient (CFC) of the Starling equation was measured with strain gauge plethysmography at calf level of lower limbs with deep venous thrombosis (DVT). CFC was significantly elevated in limbs with DVT compared to the contralateral limb (0.0037(0.0005) ml min-1 100 g-1 mmHg-1 rise in filtration pressure and 0.0026(0.0010) ml min-1 100 g-1 mmHg-1 rise in filtration pressure, p less than 0.01) (Mean(SD]. Calf blood flow was also measured with strain-gauge plethysmography and was significantly increased in limbs with DVT compared to the contralateral (2.9(1.4)ml min-1 100 g-1 and 2.3(1.4) ml min-1 100 g-1, p less than 0.05). Increased venous pressure (Pv) found in lower limbs with DVT could be expected to lead to reduced blood flow. Our results point to an inflammatory reaction over-ruling increased venous resistance. No correlation was found between CFC and blood flow but this may have methodological explanations since increased Pv will influence both CFC and blood flow recordings obtained with plethysmography. Interstitial fluid hydrostatic pressure (Pif) measured with the 'wick-in-needle' technique in the deep posterior muscle compartment was significantly increased compared to the contralateral limb (6.3(3.5) mmHg and -1.2(3.4) mmHg, p less than 0.001). No correlation was found between CFC and Pif. Increase in CFC and blood flow at calf level is probably important in oedema in lower limbs with DVT. |
| | |
Authors:
|
E Seem; E Stranden |
Related Documents
:
|
2130363 - The effect of vasodilator therapy on the limb circulation in hypertension. 7083753 - Sympathetic reflex control of subcutaneous blood flow in tetraplegic man during postura... 17637143 - Can peripheral venous blood gases replace arterial blood gases in emergency department ... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Scandinavian journal of clinical and laboratory investigation Volume: 50 ISSN: 0036-5513 ISO Abbreviation: Scand. J. Clin. Lab. Invest. Publication Date: 1990 May |
Date Detail:
|
Created Date: 1990-07-16 Completed Date: 1990-07-16 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0404375 Medline TA: Scand J Clin Lab Invest Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 331-6 Citation Subset: IM |
Affiliation:
|
Department of Vascular Surgery, Aker Hospital, Oslo, Norway. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Blood Flow Velocity Capillaries / physiopathology* Female Humans Hydrostatic Pressure Male Middle Aged Muscles / blood supply, physiopathology Plethysmography Thrombophlebitis / physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Transcapillary forces in muscle compartments of lower limbs with deep venous thrombosis.
Next Document: Decreased concentrations of deoxycholic acid in serum of uraemic patients with diarrhoea.