Document Detail

Transbronchial fine needle aspiration of the mediastinum. Importance of lymphocytes as an indicator of specimen adequacy.
MedLine Citation:
PMID:  2375220     Owner:  NLM     Status:  MEDLINE    
To determine the effectiveness and accuracy of transbronchial fine needle aspiration of mediastinal masses for the staging of bronchogenic carcinoma, the results and histologic correlations of 97 transbronchial aspirates submitted from 78 patients over a two-year period were reviewed. Malignant cells were present in 25 of 97 aspirates. Of the remaining 75 nonmalignant aspirates, 34 had corresponding mediastinal tissue sections. Review of these 34 aspirates disclosed respiratory epithelial cells without lymphocytes in 20, lymphocytes without respiratory cells in 1 and both cell types in 8. Neither cell type was present in five aspirates. The predictive value of a negative result was 78% for nonmalignant aspirates containing lymphocytes and 36% for nonmalignant aspirates not containing lymphocytes (P less than .05). The presence of lymphocytes in transbronchial needle aspirates of the mediastinum is an essential criterion of specimen adequacy. Negative specimens lacking lymphocytes should be considered unsatisfactory, regardless of the numbers of respiratory epithelial cells present.
J J Baker; P H Solanki; D A Schenk; C Van Pelt; I Ramzy
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  34     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1990 Jul-Aug
Date Detail:
Created Date:  1990-08-28     Completed Date:  1990-08-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  517-23     Citation Subset:  IM    
Department of Pathology, Willford Hall USAF Medical Center, Lackland Air Force Base, Texas.
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MeSH Terms
Adenocarcinoma / pathology
Biopsy, Needle / methods
Carcinoma / pathology
Carcinoma, Bronchogenic / pathology*
Carcinoma, Squamous Cell / pathology
Lung Neoplasms / pathology*
Lymphocytes / pathology*
Mediastinum / pathology*
Neoplasm Staging

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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