Document Detail

Transarterial and transvenous embolization for cavernous sinus dural arteriovenous fistulae.
MedLine Citation:
PMID:  20977859     Owner:  NLM     Status:  MEDLINE    
We report on the safety and efficacy of trans-arterial and transvenous Onyx embolization in the treatment of dural arteriovenous fistulae (DAVFs) of the cavernous sinus. We reviewed the findings from a retrospectively database for 22 patients with cavernous sinus DAVFs who were treated with either transarterial Onyx embolization alone (n = 8) or transarterial and transvenous Onyx embolization (n = 14) over a four year period. The mean follow-up period after endovascular treatment was 21.6 months (range 3-42 mths). Total number of embolizations was 27 for 22 patients. Two patients were treated transvenously after transarterial embolization. All 22 patients (100%) experienced improvement of their clinical symptoms. All 22 patients (100%) experienced total obliteration of their DAVFs, as documented by angiography performed at a mean follow-up of 5.8 months after the last treatment. No patient experienced a recurrence of symptoms after angiography showed DAVF obliteration. One patient exhibited temporary deterioration of ocular symptoms secondary to venous hypertension after near total obliteration; one had transient V cranial nerve deficit related to transarterial embolization, and two patients exhibited transient III and VI cranial nerve weakness related to transvenous embolization. Two patients experienced recurrent symptoms after incomplete transarterial embolization and underwent transvenous embolization at three and four months. Both patients achieved clinical and angiographic cures. Transarterial and transvenous embolization with Onyx, whenever possible, proved to be a safe and effective management for patients with cavernous sinus DAVFs.
J Zhang; X Lv; C Jiang; Y Li; X Yang; Z Wu
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-10-25
Journal Detail:
Title:  Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences     Volume:  16     ISSN:  1591-0199     ISO Abbreviation:  Interv Neuroradiol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-10-27     Completed Date:  2010-12-30     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  9602695     Medline TA:  Interv Neuroradiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  269-77     Citation Subset:  IM    
Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
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MeSH Terms
Cavernous Sinus / radiography*
Central Nervous System Vascular Malformations / radiography*,  therapy*
Cerebral Angiography
Cerebral Arteries / radiography
Cerebral Veins / radiography
Databases, Factual
Dimethyl Sulfoxide
Embolization, Therapeutic / methods*
Middle Aged
Retrospective Studies
Treatment Outcome
Reg. No./Substance:
0/Onyx copolymer; 0/Polyvinyls; 67-68-5/Dimethyl Sulfoxide

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