| Trans-thoracic fluid shifts and endocrine responses to 6 degrees head-down tilt. | |
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MedLine Citation:
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PMID: 1837213 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A tomographic method of measuring electrical impedance known as Applied Potential Tomography (APT) has been used to image the impedance changes within the thoraxes of 8 healthy volunteers (4 male, 4 female) during 4-h periods of 6 degrees head-down tilt (HDT). A large decrease in impedance, reflecting an increase in thoracic fluid, was apparent within 1 min of tilting, peaked after 45 min, and was maintained throughout, although during the 4 h there was an 8% return towards baseline resistivity. Resistivity changes were most obvious in the region of the lungs. Simultaneous measurements of the key fluid regulating hormones revealed a significant increase in atrial natriuretic peptide (ANP) and a significant decrease in angiotensin II (AII) and aldosterone. There was no significant difference in plasma antidiuretic hormone level. These results illustrate the dynamic nature of fluid shifts during HDT, the spatial distribution of the fluid within the thorax and the associated endocrine responses. |
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Authors:
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D Grundy; K Reid; F J McArdle; B H Brown; D C Barber; C F Deacon; I W Henderson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Aviation, space, and environmental medicine Volume: 62 ISSN: 0095-6562 ISO Abbreviation: Aviat Space Environ Med Publication Date: 1991 Oct |
Date Detail:
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Created Date: 1992-02-13 Completed Date: 1992-02-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7501714 Medline TA: Aviat Space Environ Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 923-9 Citation Subset: IM; S |
Affiliation:
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Department of Biomedical Science, University of Sheffield, England. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aldosterone / blood* Angiotensin II / blood* Atrial Natriuretic Factor / blood* Blood Volume / physiology Body Fluids / physiology* Electric Conductivity Female Gravitation* Heart Rate Homeostasis Humans Lung / physiology Male Posture* Sex Factors Space Flight Thorax / physiology* Time Factors Tomography / methods |
| Chemical | |
Reg. No./Substance:
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11128-99-7/Angiotensin II; 52-39-1/Aldosterone; 85637-73-6/Atrial Natriuretic Factor |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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