Document Detail


Trans-abdominal monitoring of fetal arterial blood oxygenation using pulse oximetry.
MedLine Citation:
PMID:  11092427     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pulse oximetry (oxygen saturation monitoring) has markedly improved medical care in many fields, including anesthesiology, intensive care, and newborn intensive care. In obstetrics, fetal heart rate monitoring remains the standard for intrapartum assessment of fetal well being. Fetal oxygen saturation monitoring is a new technique currently under development. It is potentially superior to electronic fetal heart rate monitoring (cardiotocography) because it allows direct assessment of both the fetal oxygen status and fetal tissue perfusion. Here we present the analysis for determining the most optimal wavelength selection for pulse oximetry. The wavelengths we chose as the most optimal are the first in the range of 670-720 nm and the second in the range of 825-925 nm. Further, we discuss the possible systematic errors during our measurements and their contribution to the obtained saturation results. We present feasibility studies for fetal pulse oximetry, monitored noninvasively through the maternal abdomen. Our preliminary experiments show that the fetal pulse can be discriminated from the maternal pulse and thus, in principle, the fetal arterial oxygen saturation can be obtained. We present the methodology for obtaining these data, and discuss the dependence of our measurements on the fetal position with respect to the optode assembly.
Authors:
A Zourabian; A Siegel; B Chance; N Ramanujan; M Rode; D A Boas
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of biomedical optics     Volume:  5     ISSN:  1083-3668     ISO Abbreviation:  J Biomed Opt     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2001-01-31     Completed Date:  2001-02-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9605853     Medline TA:  J Biomed Opt     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  391-405     Citation Subset:  IM    
Affiliation:
Tufts University, Electro-Optics and Bioengineering Department, Medford, Massachusetts 02155, USA. azoura01@emerald.tufts.edu
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MeSH Terms
Descriptor/Qualifier:
Abdomen
Computer Simulation
Feasibility Studies
Female
Fetal Blood / metabolism*
Fetal Monitoring / methods*
Humans
Oximetry*
Oxygen / blood*
Pilot Projects
Pregnancy
Spectroscopy, Near-Infrared / methods
Grant Support
ID/Acronym/Agency:
1R43HL61057-01/HL/NHLBI NIH HHS; R29NS37053/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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