Document Detail

Tramadol-associated pericarditis.
MedLine Citation:
PMID:  15771942     Owner:  NLM     Status:  MEDLINE    
Tramadol, marketed as Ultram in the United States, is as a non-scheduled narcotic analgesic based on its low abuse liability. It is indicated for the treatment of moderately severe pain; however, multiple adverse effects have been reported with its use including seizures, anaphylaxis, angioedema, bronchospasm, and serotonin syndrome. An association between tramadol and pericarditis has not been previously reported. We describe the case of an 88 year-old male who developed acute pericarditis 2 days following tramadol initiation. The temporal relationship between drug initiation and pericarditis as well as the resolution of symptoms upon drug discontinuation suggested a potential association. Although pericarditis has not been described with tramadol administration, clinicians should be aware of a possible association.
M J Krantz; J A Garcia; P S Mehler
Publication Detail:
Type:  Letter    
Journal Detail:
Title:  International journal of cardiology     Volume:  99     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-17     Completed Date:  2005-07-15     Revised Date:  2006-07-12    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  497-8     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Analgesics, Opioid / adverse effects*
Pericarditis / chemically induced*,  diagnosis
Tramadol / adverse effects*
Reg. No./Substance:
0/Analgesics, Opioid; 27203-92-5/Tramadol

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