Document Detail

Trait anger, hostility, serum homocysteine, and recurrent cardiac events after percutaneous coronary interventions.
MedLine Citation:
PMID:  19880957     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Trait anger, hostility, and serum level of homocysteine are associated with recurrent cardiac events after percutaneous coronary interventions. However, whether trait anger or hostility influences the association between serum level of homocysteine and recurrent cardiac events is unknown.
OBJECTIVES: To examine the relationships among trait anger, hostility, serum level of homocysteine, and recurrent cardiac events after percutaneous coronary interventions.
METHODS: This prospective study included 135 consecutive patients (68% male, mean age 61 [SD, 10] years) undergoing percutaneous coronary interventions during an index hospitalization. Trait anger and hostility were measured with the Spielberger Trait Anger Scale and the Cynical Hostility Scale, respectively. Blood samples were obtained to measure serum levels of total cholesterol, triglycerides, high- and low-density lipoprotein cholesterol, and homocysteine. Recurrent cardiac events (emergency department visits and rehospitalization) were noted for 6 months after discharge and confirmed by review of hospital records. Hierarchical Cox hazard regression was used for statistical analysis.
RESULTS: Trait anger (hazard ratio = 1.11, 95% confidence interval = 1.03-1.20) and homocysteine level (hazard ratio = 1.10, 95% confidence interval = 1.01-1.21) were independent predictors of recurrent cardiac events after other risk factors were controlled for. Patients with high trait anger (score > or = 24) and high serum level of homocysteine (> or = 11.3 mumol/L) had the shortest time to recurrent cardiac events (P = .01).
CONCLUSION: Trait anger had a combined effect on the link between serum level of homocysteine and recurrent cardiac events. Interventions to reduce trait anger may improve health outcomes by influencing both trait anger and homocysteine level.
Eun Kyeung Song; Youn-Jung Son; Terry A Lennie
Related Documents :
1172987 - Diagnosis of acute myocardial infarction. relative efficiency of serum enzyme and isoen...
10441107 - Decreased sodium and increased transient outward potassium currents in iron-loaded card...
12693787 - Epilepsy, atherosclerosis, myocardial infarction, and carbamazepine.
14336787 - Ischemic heart disease: use of serum enzyme determinations in diagnosis.
18358087 - Possible arrhythmiogenic mechanism produced by ibuprofen.
15954507 - Distribution of pleural effusion in congestive heart failure: what is atypical?
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  American journal of critical care : an official publication, American Association of Critical-Care Nurses     Volume:  18     ISSN:  1937-710X     ISO Abbreviation:  Am. J. Crit. Care     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-02     Completed Date:  2010-01-14     Revised Date:  2014-06-16    
Medline Journal Info:
Nlm Unique ID:  9211547     Medline TA:  Am J Crit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  554-61     Citation Subset:  IM; N    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Angioplasty, Balloon, Coronary*
Coronary Artery Disease / therapy
Coronary Disease / blood*,  psychology*
Homocysteine / blood*
Lipids / blood
Middle Aged
Prospective Studies
Risk Factors
Grant Support
Reg. No./Substance:
0/Lipids; 0LVT1QZ0BA/Homocysteine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Positive effects of a nursing intervention on family-centered care in adult critical care.
Next Document:  Marital status as an independent predictor of event-free survival of patients with heart failure.