Document Detail

Training rather than walking: the test in -train out program for home-based rehabilitation in peripheral arteriopathy.
MedLine Citation:
PMID:  18503221     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Exercise training reduces walking disability in peripheral arterial disease (PAD). This non-randomized study evaluates the effects on walking ability and hemodynamic parameters of a novel approach to home-based rehabilitation, the test in -train out program (Ti-To), compared with the traditional home-based free walking exercise (Tr-E). METHODS AND RESULTS: A total of 143 patients with claudication (117 men, average age 68+/-10 years), were included in a Ti-To (n=83) or Tr-E program (n=60). Evaluations, which were carried out upon entry and at 1, 2, 3, 4 and 6 months, included: self-reported claudication, walking ability (ie, absolute claudication distance, pain threshold speed), resting/exercise heart rates (HR), systolic/diastolic brachial pressure (SBP/DBP), ankle pressure (AP), ankle-brachial index (ABI). Ti-To involved 2 daily 10-min home walking sessions at maximal asymptomatic speed and the patient attending monthly check-ups at hospital. Tr-E involved 20-30 min of daily walking at self-selected speeds up to pain tolerance. A total of 126 patients (Ti-To, n=74; Tr-E, n=52) completed the program. Ti-To induced better relief from claudication (p=0.001). Functional parameters improved significantly for both groups (p<0.0001) with significant intergroup difference for Ti-To (p<0.0001). SBP and exercise HR decreased significantly in both groups, with Ti-To improving resting HR (p=0.0002), DBP (p=0.003), lowest AP worse limb (p=0.004) and ABI worse limb (p=0.0002). CONCLUSIONS: In patients with PAD, a Ti-To program had more positive effects on perceived claudication, and functional and hemodynamic parameters than did a Tr-E program.
Fabio Manfredini; Anna Maria Malagoni; Francesco Mascoli; Simona Mandini; Maria Cristina Taddia; Nino Basaglia; Roberto Manfredini; Francesco Conconi; Paolo Zamboni
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  72     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-26     Completed Date:  2008-09-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  946-52     Citation Subset:  IM    
Center of Biomedical Studies Applied to Sport, University of Ferrara, Ferrara, Italy.
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MeSH Terms
Ankle Joint / ultrasonography
Blood Pressure
Brachial Artery / ultrasonography
Exercise Test
Exercise Therapy
Heart Rate
Intermittent Claudication / physiopathology,  rehabilitation*,  therapy
Middle Aged
Peripheral Vascular Diseases / physiopathology,  rehabilitation*,  therapy
Physical Fitness*
Regional Blood Flow
Treatment Outcome

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