Document Detail

Training induced changes in the fatty acid composition of skeletal muscle lipids. Functional aspects.
MedLine Citation:
PMID:  9781321     Owner:  NLM     Status:  MEDLINE    
Insulin sensitivity relates to the fatty acid composition of the skeletal muscle phospholipids and the intramuscular triglyceride content. The fatty acid composition of the phospholipids--but not of the triglycerides--in the muscles are influenced by regular physical activity of low-moderate intensity. An increased degree of unsaturation of the cell membranes after training may hypothetically contribute to the improvement of insulin sensitivity. Different ways of reducing the supply of lipids in the muscles may possibly cause similar changes of the fatty acid composition of the cell membranes. Further studies are needed to explore the relationships between changes of the skeletal muscle lipid composition during physical activity, the interaction with dietary fat intake, and changes of insulin sensitivity and development of related metabolic disorders.
B Vessby; A Andersson; A Sjödin
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  441     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  1998  
Date Detail:
Created Date:  1998-12-01     Completed Date:  1998-12-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  139-45     Citation Subset:  IM; S    
Department of Geriatrics, Uppsala University, Sweden.
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MeSH Terms
Dietary Fats / metabolism
Fatty Acids / chemistry,  metabolism*
Lipid Metabolism*
Lipids / chemistry
Muscle, Skeletal / metabolism*
Physical Conditioning, Animal*
Reg. No./Substance:
0/Dietary Fats; 0/Fatty Acids; 0/Lipids

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