| Traditional uses, phytochemistry and pharmacology of Clerodendron glandulosum Coleb - a review. | |
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MedLine Citation:
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PMID: 22182635 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Present review for the first time provides a complete botanical description and information on ethnomedicinal uses of Clerodendron glandulosum.Coleb (CG; Fam, Verbenaceae). Recent studies conducted from our laboratory provide pharmacological evidence for its anti-hypertensive, anti-diabetic and anti-obesity potentials. Further, its beneficial potential in preventing in vitro and in vivo non-alcoholic steatohepatitis and atherosclerosis and potent hepatoprotective and free radical scavenging abilities along with its acute and sub-chronic toxicological evaluations are also reported from our laboratory. In keeping with its traditional uses, CG extract was capable of ameliorating experimentally induced hypertension, diabetes and obesity. Its beneficial potential against NASH induced oxidative stress and atherosclerosis can be attributed to its potent free radical scavenging potential. Non-toxic nature of CG leaf extract further provides added merit to its reported pharmacological properties. The present review summarizes the pioneering scientific evidence for the pharmacological effects of CG against related metabolic disorders like hypertension, diabetes and obesity along with anti oxidant potential and beneficial effects against non alcoholic steatohepatitis. |
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Authors:
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Ravirajsinh N Jadeja; Menaka C Thounaojam; Thouchom Brojendro Singh; Ranjitsinh V Devkar; Av Ramachandran |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Asian Pacific journal of tropical medicine Volume: 5 ISSN: 1995-7645 ISO Abbreviation: Asian Pac J Trop Med Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2011-12-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101533720 Medline TA: Asian Pac J Trop Med Country: Singapore |
Other Details:
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Languages: eng Pagination: 1-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Hainan Medical College. Published by Elsevier B.V. All rights reserved. |
Affiliation:
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Division of Phytotherapeutics and Metabolic Endocrinology, Department of Zoology, Faculty of Science, The MS University of Baroda, Vadodara-390002, Gujarat, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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