Document Detail

Tractography Demonstrates Dentate-rubro-thalamic Tract Disruption in an Adult with Cerebellar Mutism.
MedLine Citation:
PMID:  23546861     Owner:  NLM     Status:  Publisher    
A 55-year-old female is presented with transient cerebellar mutism caused by a well-circumscribed left pontine infarction due to postoperative basilar perforator occlusion. Although conventional T2 imaging shows a well-demarcated lesion confined to the pontine region, diffusion tensor imaging shows an asymmetry in fractional anisotropy in the superior cerebellar peduncle. This supports the general hypothesis that cerebellar mutism is caused by functional disruption of the dentate-rubro-thalamic tract. Correlating postoperative anatomic changes to a heterogenic clinical syndrome remains challenging, however.
Kirsten van Baarsen; Michiel Kleinnijenhuis; Tom Konert; Anne-Marie van Cappellen van Walsum; André Grotenhuis
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-4-3
Journal Detail:
Title:  Cerebellum (London, England)     Volume:  -     ISSN:  1473-4230     ISO Abbreviation:  Cerebellum     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-4-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101089443     Medline TA:  Cerebellum     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Neurosurgery, Radboud University Nijmegen Medical Centre, Huispost 636 Neurochirurgie, Postbus 9101, 6500 HB, Nijmegen, The Netherlands,
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