Document Detail

Tract-specific analysis for investigation of Alzheimer disease: a brief review.
MedLine Citation:
PMID:  20799014     Owner:  NLM     Status:  MEDLINE    
Magnetic resonance diffusion tensor imaging is a noninvasive technique that can identify white matter tracts by evaluating bulk diffusion of water in three dimensions and can thus describe the microarchitectural characteristics of local brain tissue. Several recent reports have shown that mapping of diffusion parameters is potentially useful for speculating about the pathology of Alzheimer disease (AD). These reports have employed image-analysis approaches, including region-of-interest measurement, voxel-based analysis, tract-based spatial statistics, and tract-specific analysis (TSA). The present review focuses on TSA to investigate AD. An overview of the changes in diffusion properties of AD measured using TSA is presented and discussed.
Yasuhiro Nakata; Shigeki Aoki; Noriko Sato; Hasina Yasmin; Yoshitaka Masutani; Kuni Ohtomo
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-08-27
Journal Detail:
Title:  Japanese journal of radiology     Volume:  28     ISSN:  1867-108X     ISO Abbreviation:  Jpn J Radiol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-27     Completed Date:  2011-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101490689     Medline TA:  Jpn J Radiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  494-501     Citation Subset:  IM    
Department of Radiology, National Center Hospital of Neurology and Psychiatry, Kodaira, Tokyo, Japan.
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MeSH Terms
Alzheimer Disease / pathology*
Diffusion Magnetic Resonance Imaging / methods*
Image Interpretation, Computer-Assisted
Imaging, Three-Dimensional
Nerve Fibers, Myelinated / pathology*

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