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Tracking microbial populations effective in reducing exposure.
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MedLine Citation:
PMID:  8565898     Owner:  NLM     Status:  MEDLINE    
Microbial ecology provides the link between basic biochemical and molecular studies on toxicity reduction by microbial metabolism and environmental studies that determine exposure. This link provides the ability to determine which microorganisms are responsible for the actual transformations in nature, thereby establishing how predictive the laboratory pathway, kinetic, regulatory, and enzyme mechanistic information is for nature. This information can be important to the rate of toxicant removal, the type and concentration of intermediate product(s), and the identification of conditions that limit effective toxicant removal. Nucleic acid-based methods now provide the main means to track important biodegrading populations. Examples of these methods are given that illustrate tracking a biodegrading microbe injected into an aquifer, following community succession in a toluene-degrading fluidized bed reactor, aiding the isolation from nature of novel biodegrading organisms, and rapidly characterizing the extent of microbial diversity in an aquifer stimulated to co-metabolize trichloroethene.
J M Tiedje; S M Thiem; A Massol-Deyá; J O Ka; M R Fries
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Environmental health perspectives     Volume:  103 Suppl 5     ISSN:  0091-6765     ISO Abbreviation:  Environ. Health Perspect.     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1996-03-07     Completed Date:  1996-03-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0330411     Medline TA:  Environ Health Perspect     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  117-20     Citation Subset:  IM    
Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA.
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MeSH Terms
Biodegradation, Environmental
Environmental Exposure*
Environmental Microbiology*
Environmental Monitoring*
Environmental Pollutants / metabolism,  toxicity*
Grant Support
Reg. No./Substance:
0/Environmental Pollutants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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Journal Information
Journal ID (nlm-ta): Environ Health Perspect
ISSN: 0091-6765
Article Information
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Print publication date: Month: 6 Year: 1995
Volume: 103 Issue: Suppl 5
First Page: 117 Last Page: 120
ID: 1519305
PubMed Id: 8565898

Tracking microbial populations effective in reducing exposure.
J M Tiedje
S M Thiem
A Massol-Dey?
J O Ka
M R Fries
Center for Microbial Ecology, Michigan State University, East Lansing 48824, USA.

Article Categories:
  • Research Article

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