| Tracheomegaly: a complication of fetal endoscopic tracheal occlusion in the treatment of congenital diaphragmatic hernia. | |
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MedLine Citation:
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PMID: 19894042 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Fetal endoscopic tracheal occlusion (FETO) is a promising treatment for severe congenital diaphragmatic hernia, a condition that carries significant morbidity and mortality. It is hypothesised that balloon occlusion of the fetal trachea leads to an improvement in lung growth and development. The major documented complications of FETO to date are related to preterm delivery. OBJECTIVE: To report a series of five infants who developed tracheomegaly following FETO. MATERIALS AND METHODS: Review of all children referred with tracheomegaly to the paediatric intensive care and tracheal service at two referral centres. RESULTS: Five neonates presented with features of respiratory distress shortly after birth and were subsequently found to have marked tracheomegaly. Two neonates had tracheomalacia in addition. CONCLUSION: There are no previous reports in the literature describing tracheomalacia, or more specifically, tracheomegaly, as a consequence of FETO. We propose that the particularly compliant fetal airway is at risk of mechanical damage from in utero balloon occlusion. This observation of a new problem in this cohort suggests a thorough evaluation of the trachea should be performed in children who have had FETO in utero. It may be that balloon occlusion of the trachea earlier in utero (before 26 weeks' gestation) predisposes to this condition. |
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Authors:
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Kieran McHugh; Asim Afaq; Nigel Broderick; Hany O Gabra; Derek J Roebuck; Martin J Elliott |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-11-06 |
Journal Detail:
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Title: Pediatric radiology Volume: 40 ISSN: 1432-1998 ISO Abbreviation: Pediatr Radiol Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-03-30 Completed Date: 2010-06-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0365332 Medline TA: Pediatr Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 674-80 Citation Subset: IM |
Affiliation:
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Radiology Department, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK. mchugk@gosh.nhs.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Endoscopy
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adverse effects* Female Fetal Diseases / radiography, surgery* Hernia, Diaphragmatic / complications, radiography, surgery* Humans Male Tracheobronchomegaly / etiology*, radiography* Tracheotomy / adverse effects* Treatment Outcome |
| Comments/Corrections | |
Comment In:
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Pediatr Radiol. 2010 May;40(5):670-3
[PMID:
20352401
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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