Document Detail


Tracheoesophageal fistula closed by chemoradiotherapy in lung cancer.
MedLine Citation:
PMID:  21769294     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A 45-year-old man complaining of cough, dyspnea, and difficulty in swallowing was referred to our hospital. Chest CT scan showed a mediastinal mass compressing the trachea. He was diagnosed with poorly differentiated lung carcinoma by percutaneous needle biopsy. Bronchoscopy and upper gastrointestinal endoscopy revealed a tracheoesophageal fistula (TEF). Long-lasting febrile neutropenia made it impossible to continue chemotherapy, but a course of radiotherapy (total 61 Gy) was completed. The next endoscopy revealed closure of the TEF. Chemoradiotherapy (CRT) has been reported to close TEF in esophageal cancer, but the risk of a CRT-induced worsening of the fistula has dissuaded physicians from using CRT to treat TEF in lung cancer patients. CRT may serve as a palliative treatment for TEF in lung cancer as well as esophageal cancer.
Authors:
Takayuki Honda; Yoshihito Tsuzaki; Keiko Mitaka; Kazuhiro Fukasawa; Yoshihiro Miyashita; Kan Marino; Akitoshi Saito; Toshio Oyama; Naohiko Inase
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Publication Detail:
Type:  Journal Article     Date:  2011-07-09
Journal Detail:
Title:  Case reports in oncology     Volume:  4     ISSN:  1662-6575     ISO Abbreviation:  Case Rep Oncol     Publication Date:  2011  
Date Detail:
Created Date:  2011-07-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101517601     Medline TA:  Case Rep Oncol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  350-7     Citation Subset:  -    
Affiliation:
Department of Respiratory Medicine, Kofu, Tokyo Medical and Dental University, Tokyo, Japan.
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