Document Detail

Tracheal mucus transport rate and bacterial clearance in turkeys exposed by aerosol to La Sota strain of Newcastle disease virus.
MedLine Citation:
PMID:  3304262     Owner:  NLM     Status:  MEDLINE    
Tracheal mucus transport rate (TMTR) and quantitative clearance of aerosolized Escherichia coli from the trachea, lung, and air sac were measured in healthy unanesthetized turkeys and in turkeys exposed by aerosol to a La Sota vaccine strain of Newcastle disease virus (NDV). The TMTR of uninfected turkeys was 42.4 +/- 14.7 cm/min. The TMTR of NDV-infected turkeys was depressed on days 3 through 7 postexposure (PE); depression was significant (P less than or equal to 0.05) on day 7 PE. Tracheal E. coli clearance in NDV-infected turkeys was reduced on days 4 through 9 PE, significantly so on day 5 PE (P less than or equal to 0.01). Depression of TMTR and tracheal E. coli clearance were associated histologically with replacement of normal pseudostratified columnar epithelium by 3 to 8 layers of immature nonciliated cells. E. coli clearance by the lung and air sac of NDV-infected turkeys was depressed on days 5 through 9 PE.
M D Ficken; J F Edwards; J C Lay; D E Tveter
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Avian diseases     Volume:  31     ISSN:  0005-2086     ISO Abbreviation:  Avian Dis.     Publication Date:    1987 Apr-Jun
Date Detail:
Created Date:  1987-09-01     Completed Date:  1987-09-01     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370617     Medline TA:  Avian Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  241-8     Citation Subset:  IM    
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MeSH Terms
Air Sacs / microbiology,  pathology
Epithelium / microbiology,  pathology
Escherichia coli / physiology*
Lung / microbiology,  pathology
Mucus / physiology*
Newcastle Disease / microbiology*,  pathology,  physiopathology
Respiratory System / microbiology*,  pathology
Trachea / microbiology,  pathology,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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