| Tracheal occlusion for fetal congenital diaphragmatic hernia: the US experience. | |
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MedLine Citation:
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PMID: 19559324 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Congenital diaphragmatic hernia (CDH) is characterized by a defect in the diaphragm that permits abdominal viscera to herniate into the chest. These herniated viscera are thought to compress the growing lung and cause lung parenchymal and vascular hypoplasia. The genetic defects that cause the diaphragmatic defect may also contribute primarily to lung hypoplasia. Postnatal reduction of the herniated abdominal viscera and correction of the diaphragmatic defect are easily achievable, but the lung hypoplasia persists, often leading to persistent fetal circulation and respiratory failure. This article reviews the experimental basis of fetal therapy for CDH and the US clinical experience with tracheal occlusion. |
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Authors:
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Eric Jelin; Hanmin Lee |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinics in perinatology Volume: 36 ISSN: 1557-9840 ISO Abbreviation: Clin Perinatol Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-29 Completed Date: 2009-10-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7501306 Medline TA: Clin Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 349-61, ix Citation Subset: IM |
Affiliation:
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Division of Pediatric Surgery, Department of Surgery, Fetal Treatment Center, University of California, San Francisco, CA 94143-0570, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Fetus / surgery* Hernia, Diaphragmatic / congenital*, diagnosis, surgery Humans Pregnancy Prenatal Diagnosis / methods* Surgical Procedures, Operative / methods* Tracheal Stenosis / diagnosis, etiology*, surgery United States |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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