| Trace of metal exposure in hard metal lung disease. | |
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MedLine Citation:
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PMID: 3720369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A male subject exposed for many years to metal dusts from grinding and cutting hard metals was investigated four years after the exposure ceased. While chest x-ray films and histologic examinations showed diffuse interstitial fibrosis and severe perivascular and peribronchiolar fibrosis, radiochemical neutron activation analysis (NAA) showed high W, Ta and Co concentrations in the pulmonary specimen compared to the corresponding determinations in 17 control subjects. Tantalum was also found in high concentrations in bronchoalveolar lavage fluid (BAL) and in the blood. In addition other elements such as Ni, Cr, Th and Cd were found in the lung biopsy specimen of the worker in amounts significantly higher than in the control subjects. The results suggest that hard metal origin of pulmonary fibrosis can be detected many years after removal from exposure. |
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Authors:
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G Rizzato; S Lo Cicero; M Barberis; M Torre; R Pietra; E Sabbioni |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Chest Volume: 90 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1986 Jul |
Date Detail:
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Created Date: 1986-08-04 Completed Date: 1986-08-04 Revised Date: 2006-04-19 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 101-6 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy Chronic Disease Dust / adverse effects, analysis Humans Irrigation Lung / analysis, pathology Lung Diseases / chemically induced*, metabolism, pathology Male Metals / adverse effects*, analysis Occupational Diseases / chemically induced*, metabolism, pathology |
| Chemical | |
Reg. No./Substance:
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0/Dust; 0/Metals |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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