Document Detail

T(peak)T(end) interval in long QT syndrome.
MedLine Citation:
PMID:  18822425     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The T(peak)T(end) (T(p)T(e)) interval is believed to reflect the transmural dispersion of repolarization. Accordingly, it should be a risk factor in long QT syndrome (LQTS). The aim of the study was to determine the effect of genotype on T(p)T(e) interval and test whether it was related to the occurrence of syncope. METHODS: Electrocardiograms were taken in 95 patients with LQTS drawn from the Danish long QT registry (44 patients with KvLQT1, 43 with HERG, and 8 with SCN5A mutations) and manually evaluated for the QT, QT(peak), and RR interval. RESULTS AND CONCLUSION: (1) T(p)T(e) cannot be used to distinguish symptomatic from asymptomatic patients with LQTS; (2) HERG patients have longer T(p)T(e) than KvLQT1 patients; and (3) there is no need to heart rate-correct T(p)T(e) intervals in patients with LQTS.
Jorgen K Kanters; Christian Haarmark; Esben Vedel-Larsen; Mads P Andersen; Claus Graff; Johannes J Struijk; Poul Erik Bloch Thomsen; Michael Christiansen; Henrik K Jensen; Egon Toft
Related Documents :
16235005 - High-dose beta-blocker hypertrophic cardiomyopathy therapy in a patient with friedreich...
9728945 - Highly abnormal thermotests in familial dysautonomia suggest increased cardiac autonomi...
17900255 - Clinical characteristics and risk stratification in symptomatic and asymptomatic patien...
10433085 - The frequency of occurrence of anti-cardiac receptor autoantibodies and their correlati...
15834305 - Cerebrospinal fluid concentrations of anti-inflammatory mediators in early-phase severe...
11574445 - Functional status of persons with diabetes-related lower-extremity amputations.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-09-25
Journal Detail:
Title:  Journal of electrocardiology     Volume:  41     ISSN:  1532-8430     ISO Abbreviation:  J Electrocardiol     Publication Date:    2008 Nov-Dec
Date Detail:
Created Date:  2008-10-28     Completed Date:  2009-01-09     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  603-8     Citation Subset:  IM    
Danish National Research Foundation Center of Arrhythmias (DARC), Copenhagen, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Denmark / epidemiology
Diagnosis, Computer-Assisted / methods*
Electrocardiography / methods*,  statistics & numerical data*
Long QT Syndrome / diagnosis*,  epidemiology*
Reproducibility of Results
Risk Assessment / methods*
Risk Factors
Sensitivity and Specificity
Syncope / diagnosis*,  epidemiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The appearance of negative U waves in the precordial leads during balloon occlusion of the long post...
Next Document:  Association between foot growth and musculoskeletal loading in children with Prader-Willi syndrome b...