| Toxicological effects of aflatoxins in horses. | |
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MedLine Citation:
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PMID: 20619706 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Aflatoxins are a group of mycotoxins principally produced by Aspergillus flavus and A. parasiticus, which are both natural contaminants of food and feedstuff. Aflatoxin B(1) is the most prevalent member of this group that is normally detected and is the most powerful hepatocarcinogen known. Few naturally occurring episodes of aflatoxicosis in horses have been reported in the literature. Indeed, the published information about aflatoxin exposure, metabolism and the effects on horses is limited and controversial, possibly indicating a lack of awareness rather than the rarity of the occurrence. The target organ in horses, as in other animal species, is the liver and horses suffering from aflatoxicosis show signs of inappetence, depression, fever, tremor, ataxia and cough. Necropsy findings include a yellow-brown liver with centrilobular necrosis, icterus, haemorrhage, tracheal exudates and brown urine. A possible link between aflatoxin exposure and chronic obstructive pulmonary disease has been hypothesised. |
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Authors:
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Francesca Caloni; Cristina Cortinovis |
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Publication Detail:
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Type: Journal Article Date: 2010-07-08 |
Journal Detail:
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Title: Veterinary journal (London, England : 1997) Volume: 188 ISSN: 1532-2971 ISO Abbreviation: Vet. J. Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-05-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9706281 Medline TA: Vet J Country: England |
Other Details:
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Languages: eng Pagination: 270-3 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Veterinary Sciences and Technologies for Food Safety, Faculty of Veterinary Medicine, Università degli Studi di Milano, Via Celoria 10, 20133 Milan, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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