| Toxicological considerations of Kampo medicines in clinical use. | |
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MedLine Citation:
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PMID: 15138045 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Kampo (Japanese herbal) medicines, produced by combining multiple crude drugs, almost all of plant origin but with some of animal or mineral origin, contain great many substances. Since Kampo medicine results from the combination of many substances, their effect is a combination of the various interactions of the constituent substances. It has been demonstrated that several potential side effects such as allergic reactions, diarrhea and vomiting may be experienced when administering Kampo medicine. In addition, it has been reported that Kampo medicine may have antagonistic or synergistic interactions with western drugs or with some foods such as grapefruit juice. Among the 210 medicinal prescriptions used in present-day Japan, the clinical uses and the acute, chronic and mutagenic toxicity of some Kampo medicines are described. Studies of some potential interaction between Kampo medicines and western drugs are also considered. |
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Authors:
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Fumio Ikegami; Yuichi Fujii; Tetsuo Satoh |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Toxicology Volume: 198 ISSN: 0300-483X ISO Abbreviation: Toxicology Publication Date: 2004 May |
Date Detail:
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Created Date: 2004-05-12 Completed Date: 2004-06-17 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0361055 Medline TA: Toxicology Country: Ireland |
Other Details:
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Languages: eng Pagination: 221-8 Citation Subset: IM |
Affiliation:
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Center for Environment, Health and Field Sciences, Chiba University, Kashiwanoha 6-2-1, Kashiwa 277-0882, Japan. ikegami@faculty.chiba.u.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Drug Interactions Drugs, Chinese Herbal / therapeutic use, toxicity* Humans Japan Medicine, Kampo* |
| Chemical | |
Reg. No./Substance:
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0/Drugs, Chinese Herbal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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