Document Detail


Toxico-surveillance of infant and toddler poisonings in the United States.
MedLine Citation:
PMID:  22528591     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Infant and toddler poisonings are important to capture and may be challenging to manage. We aim to describe the Toxicology Investigators Consortium (ToxIC) Case Registry as a tool for toxico-surveillance of this problem in the United States. Using the ToxIC Case Registry database of the American College of Medical Toxicology, we identified infant and toddler poisonings over a 15-month period between April 1, 2010 and June 30, 2011 reported to the 31 Registry sites. Of 6,810 poisoning cases reported to the ToxIC registry, 248 (3.6 %) involved children younger than 2 years (51 % males). Fifty-four percent were hospital inpatients, 42 % were in the Emergency Department and 4 % were outpatients. Sixty-three percent were symptomatic. The most common ingested compounds were highly toxic-cardiac drugs (16 %), psychotropics (15 %), recreational drugs, alcohols, and controlled narcotic drugs (13 %), analgesics (9 %), and cleaning compounds (7 %). Fourteen percent of cases involved multiple agents. The ToxIC registry is a potentially useful toxico-surveillance tool to identify and trend clinically significant poisonings in young children, and potentially other populations. These data could be used to target specific preventive interventions.
Authors:
Yaron Finkelstein; Janine R Hutson; Paul M Wax; Jeffrey Brent;
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of medical toxicology : official journal of the American College of Medical Toxicology     Volume:  8     ISSN:  1937-6995     ISO Abbreviation:  J Med Toxicol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-20     Completed Date:  2013-02-12     Revised Date:  2013-09-03    
Medline Journal Info:
Nlm Unique ID:  101284598     Medline TA:  J Med Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  263-6     Citation Subset:  IM    
Affiliation:
Division of Emergency Medicine, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada. Yaron.Finkelstein@sickkids.ca
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MeSH Terms
Descriptor/Qualifier:
Anticonvulsants / toxicity
Antidepressive Agents / toxicity
Antipsychotic Agents / toxicity
Cardiovascular Agents / toxicity
Cohort Studies
Drug Toxicity / epidemiology*
Emergency Service, Hospital
Female
Hospitalization
Humans
Infant
Inpatients
Male
Outpatients
Poisoning / epidemiology*
Prospective Studies
Psychotropic Drugs / toxicity
Registries*
Toxicology
United States / epidemiology
Chemical
Reg. No./Substance:
0/Anticonvulsants; 0/Antidepressive Agents; 0/Antipsychotic Agents; 0/Cardiovascular Agents; 0/Psychotropic Drugs
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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