| Toxicity to topical dimethyl sulfoxide in a pediatric patient with anthracycline extravasation. | |
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MedLine Citation:
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PMID: 15770831 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Accidental extravasation of vesicant chemotherapy may cause important tissue injuries. Nowadays, the majority of authors propose topical dimethyl sulfoxide (DMSO), with or without local cooling, as the treatment of choise efor anthracyclines extravasation. No significant toxicity has been reported when DMSO is used as topical treatment. This report describes a case of local toxicity consisting of severe pain after its use in a pediatric patient. An illustration shows the extravasation area. |
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Authors:
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M E Llinares; M Bermúdez; J L Fuster; M S Diaz; C M Gonzalez |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric hematology and oncology Volume: 22 ISSN: 0888-0018 ISO Abbreviation: Pediatr Hematol Oncol Publication Date: 2005 Jan-Feb |
Date Detail:
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Created Date: 2005-03-17 Completed Date: 2005-09-27 Revised Date: 2006-04-24 |
Medline Journal Info:
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Nlm Unique ID: 8700164 Medline TA: Pediatr Hematol Oncol Country: England |
Other Details:
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Languages: eng Pagination: 49-52 Citation Subset: IM |
Affiliation:
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Division of Hematology Oncology, Pediatric Department, University Hospital Virgen de la Arrixaca, Murcia, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibiotics, Antineoplastic
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administration & dosage,
adverse effects Antineoplastic Combined Chemotherapy Protocols / administration & dosage, adverse effects* Child, Preschool Dimethyl Sulfoxide / adverse effects*, therapeutic use Extravasation of Diagnostic and Therapeutic Materials / drug therapy* Female Humans Leukemia, Myelomonocytic, Acute / drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Antibiotics, Antineoplastic; 67-68-5/Dimethyl Sulfoxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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