Document Detail


Toxicity of fluorotelomer carboxylic acids to the algae Pseudokirchneriella subcapitata and Chlorella vulgaris, and the amphipod Hyalella azteca.
MedLine Citation:
PMID:  21872332     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Perfluorinated acids (PFAs) have elicited significant global regulatory and scientific concern due to their persistence and global pervasiveness. A source of PFAs in the environment is through degradation of fluorotelomer carboxylic acids (FTCAs) but little is known about the toxicity of these degradation products. Previous work found that FTCAs were two to three orders of magnitude more toxic to some freshwater invertebrates than their PFA counterparts and exhibited comparable chain-length-toxicity relationships. In this study, we investigated the toxicity of the 6:2, 8:2, and 10:2 saturated (FTsCA) and unsaturated (FTuCA) fluorotelomer carboxylic acids to two species of freshwater algae, Chlorella vulgaris and Pseudokirchneriella subcapitata, and the amphipod, Hyalella azteca. C. vulgaris was generally the most sensitive species, with EC(50)s of 26.2, 31.8, 11.1, and 4.2mg/L for the 6:2 FTsCA, 6:2 FTuCA, 8:2 FTuCA, and 10:2 FTsCA, respectively. H. azteca was most sensitive to the 8:2 FTsCA and 10:2 FTuCA, with LC(50)s of 5.1 and 3.7mg/L. The toxicity of the FTCAs generally increased with increasing carbon chain length, and with saturation for most of the species tested, with the exception of P. subcapitata, which did not exhibit any trend. These observations agree with chain-length-toxicity relationships previously reported for the PFCAs and support the greater toxicity of the FTCAs compared to PFCAs. However, the toxicity values are approximately 1000-fold above those detected in the environment indicating negligible risk to aquatic invertebrates.
Authors:
Rebecca J Mitchell; Anne L Myers; Scott A Mabury; Keith R Solomon; Paul K Sibley
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-25
Journal Detail:
Title:  Ecotoxicology and environmental safety     Volume:  -     ISSN:  1090-2414     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7805381     Medline TA:  Ecotoxicol Environ Saf     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
School of Environmental Sciences, University of Guelph, Guelph, ON, Canada N1G 2W1.
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